METHYLENE BLUE (METHYLTHIONINIUM CHLORIDE)

C.I. Basic Blue 3 [Basic Blue BG] CAS RN.:33203-82-6 COLOR INDEX:42775, 51004 FORMULA:C20H26ClN3O H.S CODE:3204.13.2500 STRENGTH:250.0% ± 10.0% U$13/kg CFR by sea for 1,000kgs U$100/kg To door by EMS for 10kgs C.I. Basic Blue 7 [Victoria Blue BO] CAS RN.:2390-60-5 COLOR INDEX:42595 FORMULA:C33H40ClN3 H.S CODE:3212.90.0000 CLASS:Triphenylmethane STRENGTH:100.0% ± 3.0% U$25/kg CFR by sea for 250kgs U$165/kg To door by EMS for 10kgs C.I. Basic Blue 9 [Methylene Blue] CAS RN.:61-73-4 COLOR INDEX:52015 FORMULA:C16H18N3S.Cl H.S CODE:3204.13.4500 STRENGTH:100.0% ± 3.0% U$16/kg CFR by sea for 500kgs U$120/kg To door by EMS for 10kgs C.I. Basic Blue 11 [Victoria Blue R] CAS RN.:2185-86-6 COLOR INDEX:44040 FORMULA:C29H32ClN3 H.S CODE:3204.13.8000 CLASS:Triphenylmethane STRENGTH:100.0% ± 3.0% U$22.5/kg CFR by sea for 250kgs U$160/kg To door by EMS for 10kgs C.I. Basic Blue 26 [Victoria Blue B] CAS RN.:2580-56-5 COLOR INDEX:44045 FORMULA:C33H32ClN3 H.S CODE:3204.13.8000 CLASS:Triphenylmethane STRENGTH:100.0% ± 3.0% U$22/kg CFR by sea for 250kgs U$160/kg To door by EMS for 10kgs C.I. Basic Blue 41 [Catonic Blue GRL] CAS RN.:12270-13-2 COLOR INDEX:11105, 11154 FORMULA:C19H23N4O2S.CH3O4S H.S CODE:3204.13.1000 CRUDE: 480% U$12/kg CFR by sea for 1,000kgs U$105/kg To door by EMS for 10kgs C.I. Basic Blue 54 [Catonic Blue 2RL] CAS RN.:15000-59-6 COLOR INDEX:11052 FORMULA:C17H19N4OS.CH3O4S H.S CODE:3204.13.1000 CRUDE: 500% U$14/kg CFR by sea for 500kgs U$110/kg To door by EMS for 10kgs C.I. Basic Blue 62 [Basic Blue 5RL] CAS RN.:12221-36-2 STRENGTH:200.0% ± 20.0% U$15/kg CFR by sea for 500kgs U$120/kg To door by EMS for 10kgs C.I. Basic Blue 159 [Basic Blue FBL] CAS RN.:105953-73-9 FORMULA:Unspecified STRENGTH:250.0% ± 3.0% U$14/kg CFR by sea for 500kgs U$110/kg To door by EMS for 10kgs C.I. Basic Blue 162 [Basic Blue FRL] CAS RN.:15085-91-3 FORMULA:C20H23N5O5S2 STRENGTH:500.0% ± 50.0% U$24/kg CFR by sea for 250kgs U$140/kg To door by EMS for 10kgs

METHYLENE BLUE
PRODUCT IDENTIFICATION
CAS NO.	61-73-4 (Anhydrous) 7220-79-3 (Trihydrate)
EINECS NO.	200-515-2
FORMULA	C₁₆H₁₈ClN₃S
MOL WT.	319.85
H.S. CODE	3204.13.4500
TOXICITY	Oral rat LD50: 1180 mg/kg
SYNONYMS	Basic blue 9; Methylthioninium chloride; Swiss blue;
3,7-Bis(dimethylamino)-phenothiazin-5-ium chloride; p-Bis(dimethylamino)-phenothiazin- 5-ium chloride; C.I. 52015; Methylthioninium chloride; 3,7-Bis(dimethylamino)phenazathionium chloride; Tetramethylene Blue; Tetramethylthionine chloride; Urolene Blue; Methylene blue; Other RN: 1341-90-8, 6476-03-5, 105504-42-5, 121067-62-7, 12262-49-6, 167498-52-4, 97130-83-1
SMILES	c12c(nc3ccc(cc3[s+]1)N(C)C)ccc(N(C)C)c2.[ClH-]
CLASSIFICATION
EXTRA NOTES	EPA Pesticide Chemical Code 039505 water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits Guanylate cyclase, and has been used to treat cyanide poisoning and to lower levels of Methemoglobin.
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	dark green crystalline powder
MELTING POINT	190 C (Decomposes)
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER	4.36E+04 mg/l
AUTOIGNITION
pH
VAPOR DENSITY
NFPA RATINGS
FLASH POINT
STABILITY	Stable under ordinary conditions. Hygroscopic
EXTERNAL LINKS & GENERAL DESCRIPTION
Wikipedia Linking - Methylene blue Google Scholar Search - Methylene blue Drug Information Portal (U.S. National Library of Medicine) - Methylene blue PubChem Compound Summary - Methylene blue KEGG (Kyoto Encyclopedia of Genes and Genomes) - Methylene blue http://www.ebi.ac.uk/ - Methylene blue http://www.ncbi.nlm.nih.gov/ - Methylene blue http://toxnet.nlm.nih.gov/ Hazardous Substances Data Bank - Methylene blue Local: Methylene blue, a methylated homologue of basic dye, is a cationic thiazine dye showing deep blue color in the oxidized state. It is a highly hygroscopic dark green crystalline powder having a bronze-like luster. It forms a reversible redox system with colorless leukomethylene blue (the reduced state of methylene blue). They exist in equilibrium. Methylene blue reduces the heme from methemoglobin to hemoglobin, but methemoglobin is produced when equilibrium is destroyed at high level of methylene blue. It is an electron donor or acceptor and free radical scavenger. It is clinically used to identify anatomic and pathologic structures to treat methemoglobinemia. It is used as a bacteriological in fresh frozen plasma. It is used to treat ich. It is used as a pathological stain and as a diagnostic aid in the detection of the premature rupture of fetal membranes and to identify separate amniotic sacs in multiple pregnancies. It is used as a biological and bacteriological stain, oxidation-reduction indicator as well.
SALES SPECIFICATION
APPEARANCE	dark green crystalline powder
DYE CONTENT	82.0% min
WATER	8 - 18.0%
SULFATED ASH	0.3% max
SOLUBILITY	430 (g/l in methanol)
HEAVY METALS	5ppm max
TRANSPORTATION
PACKING
HAZARD CLASS	Not regulated
UN NO.
OTHER INFORMATION
`Hazard Symbols: XN, Risk Phrases: 40, Safety Phrases: 24/25/36/37/45`
BIOLOGICAL STAINS, INDICATORS
SAFETY INFORMATION
HAZARD OVERVIEW	Harmful if swallowed. Target Organ Effect, Harmful by ingestion., Irritant. Target Organs:Blood, Central nervous system, Eyes
GHS
SIGNAL WORD	Warning
PICTOGRAMS
HAZARD STATEMENTS	H302-H315-H319-H335
P STATEMENTS	P261-P305 + P351 + P338
EC DIRECTIVES
HAZARD CODES
RISK PHRASES	22-36/37/38
SAFETY PHRASES	26-36